Jump to publication list 1996.Jump to publication list 1999.Jump to publication list 1998.Jump to publication list 1997.
Publications 2005 down
 

  • Zweers MC, Dean WB, van Kuppevelt TH, Bristow J, Schalkwijk J (2005) Elastic fiber abnormalities in hypermobility type Ehlers-Danlos syndrome patients with tenascin-X mutations. Clin.Genet. 67, 330-334.
     

  • Zweers MC, Kucharekova M, Schalkwijk J (2005) Tenascin-X: a candidate gene for benign joint hypermobility syndrome and hypermobility type Ehlers-Danlos syndrome? Ann.Rheum.Dis. 64, 504-505.
     

  • Vos JB, van Sterkenburg MA, Rabe KF, Schalkwijk J, Hiemstra PS, Datson NA (2005) THE TRANSCRIPTIONAL RESPONSE OF BRONCHIAL EPITHELIAL CELLS TO PSEUDOMONAS AERUGINOSA: IDENTIFICATION OF EARLY MEDIATORS OF HOST DEFENSE. Physiol Genomics .
     

  • Vissers WH, Roelofzen J, De Jong EM, Van Erp PE, Van de Kerkhof PC (2005) Flexural versus plaque lesions in psoriasis: an immunohistochemical differentiation. Eur.J.Dermatol. 15, 13-17.
     

  • van Duijnhoven MW, Van de Kerkhof PC, Pasch MC, Muys L, Van Erp PE (2005) The combination of the Zenon labeling technique and microscopic image analysis to study cell populations in normal and psoriatic epidermis. J.Cutan.Pathol. 32, 212-219.
     

  • Franssen ME, Zeeuwen PL, Vierwinden G, Van de Kerkhof PC, Schalkwijk J, Van Erp PE (2005) Phenotypical and functional differences in germinative subpopulations derived from normal and psoriatic epidermis. J.Invest Dermatol. 124, 373-383.
     

  • Zweers MC, Schalkwijk J, van Kuppevelt TH, van Vlijmen-Willems IM, Bergers M, Lethias C, Lamme EN (2005) Transplantation of reconstructed human skin on nude mice: a model system to study expression of human tenascin-X and elastic fiber components. Cell Tissue Res. 319, 279-287.
     

  • Jansen BJ, de JG, Schalkwijk J, van RF (2005) Serial analysis of gene expression in human keratinocytes and epidermis. Methods Mol.Biol. 289, 383-398.
     

  • Van Erp PE (2005) Proliferation, differentiation, and inflammation in normal and hyperproliferative skin using multiparameter flow cytometry. Methods Mol.Biol. 289, 239-250.

   
Publications 2004 up down
 

  • Zeeuwen PL (2004) Epidermal differentiation: The role of proteases and their inhibitors. Eur.J.Cell Biol. 83, 761-773
     

  • Wang H, Van Blitterswijk CA, Bertrand-De HM, Schuurman AH, Lamme EN (2004) Improved enzymatic isolation of fibroblasts for the creation of autologous skin substitutes. In Vitro Cell Dev.Biol.Anim 40, 268-277.
     

  • Zweers MC, van Vlijmen-Willems IM, van Kuppevelt TH, Mecham RP, Steijlen PM, Bristow J, Schalkwijk J (2004) Deficiency of tenascin-X causes abnormalities in dermal elastic fiber morphology. J.Invest Dermatol. 122, 885-891.
     

  • Zweers MC, Hakim AJ, Grahame R, Schalkwijk J (2004) Joint hypermobility syndromes: the pathophysiologic role of tenascin-X gene defects. Arthritis Rheum. 50, 2742-2749.

  • Zeeuwen PL, van Vlijmen-Willems IM, Olthuis D, Johansen HT, Hitomi K, Hara-Nishimura I, Powers JC, James KE, op den Camp HJ, Lemmens R, Schalkwijk J (2004) Evidence that unrestricted legumain activity is involved in disturbed epidermal cornification in cystatin M/E deficient mice. Hum.Mol.Genet. 13, 1069-1079.

  • Wang HJ, Pieper J, Schotel R, van Blitterswijk CA, Lamme EN (2004) Stimulation of skin repair is dependent on fibroblast source and presence of extracellular matrix. Tissue Eng 10, 1054-1064.

  • Vissers WH, Arndtz CH, Muys L, van Erp PE, de Jong EM, van de Kerkhof PC (2004) Memory effector (CD45RO+) and cytotoxic (CD8+) T cells appear early in the margin zone of spreading psoriatic lesions in contrast to cells expressing natural killer receptors, which appear late. Br.J.Dermatol. 150, 852-859.

  • Vissers WH, Berends M, Muys L, van Erp PE, de Jong EM, van de Kerkhof PC (2004) The effect of the combination of calcipotriol and betamethasone dipropionate versus both monotherapies on epidermal proliferation, keratinization and T-cell subsets in chronic plaque psoriasis. Exp.Dermatol.  13, 106-112.

  • van Steensel MA, Steijlen PM, Bladergroen RS, Hoefsloot EH, van Ravenswaaij-Arts CM, van GM (2004) A phenotype resembling the Clouston syndrome with deafness is associated with a novel missense GJB2 mutation. J.Invest Dermatol. 123, 291-293.

  • van Rossum MM, Franssen ME, Cloin WA, van de Bosch GJ, Boezeman JB, Schalkwijk J, van de Kerkhof PC, van Erp PE (2004) Functional characterization of beta1-integrin-positive epidermal cell populations. Acta Derm.Venereol. 84, 265-270.

  • van den Bogaerdt AJ, Ulrich MM, van Galen MJ, Reijnen L, Verkerk M, Pieper J, Lamme EN, Middelkoop E (2004) Upside-down transfer of porcine keratinocytes from a porous, synthetic dressing to experimental full-thickness wounds. Wound.Repair Regen. 12, 225-234.

  • van de Kerkhof PC (2004) The impact of a two-compound product containing calcipotriol and betamethasone dipropionate (Daivobet/ Dovobet) on the quality of life in patients with psoriasis vulgaris: a randomized controlled trial. Br.J.Dermatol. 151, 663-668.

  • Smetsers TF, van de Westerlo EM, ten Dam GB, Overes IM, Schalkwijk J, van Muijen GN, van Kuppevelt TH (2004) Human single-chain antibodies reactive with native chondroitin sulfate detect chondroitin sulfate alterations in melanoma and psoriasis. J.Invest Dermatol. 122, 707-716.

  • Peeters AC, Kucharekova M, Timmermans J, van den Berkmortel FW, Boers GH, Novakova IR, Egging D, den HM, Schalkwijk J (2004) A clinical and cardiovascular survey of Ehlers-Danlos syndrome patients with complete deficiency of tenascin-X. Neth.J.Med. 62, 160-162.

  • Niessen FB, Schalkwijk J, Vos H, Timens W (2004) Hypertrophic scar formation is associated with an increased number of epidermal Langerhans cells. J.Pathol. 202, 121-129.

  • Middelkoop E, van den Bogaerdt AJ, Lamme EN, Hoekstra MJ, Brandsma K, Ulrich MM (2004) Porcine wound models for skin substitution and burn treatment. Biomaterials 25, 1559-1567.

  • Franssen ME, de Jongh GJ, van Erp PE, van de Kerkhof PC (2004) A left/right comparison of twice-daily calcipotriol ointment and calcitriol ointment in patients with psoriasis: the effect on keratinocyte subpopulations. Acta Derm.Venereol. 84, 195-200.

  • Franssen ME, Boezeman JB, van de Kerkhof PC, van Erp PE (2004) Monitoring hyperproliferative disorders in human skin: flow cytometry of changing cytokeratin expression. Cytometry 57B,  32-39.

  • El-Ghalbzouri A, Lamme EN, van BC, Koopman J, Ponec M (2004) The use of PEGT/PBT as a dermal scaffold for skin tissue engineering. Biomaterials 25, 2987-2996.

  • Druecke D, Lamme EN, Hermann S, Pieper J, May PS, Steinau HU, Steinstraesser L (2004) Modulation of scar tissue formation using different dermal regeneration templates in the treatment of experimental full-thickness wounds. Wound.Repair Regen. 12, 518-527.

   
Publications 2003 up down
 

  • Jansen,B.J., van Ruissen,F., Cerneus,S., Cloin,W., Bergers,M., van Erp,P.E. & Schalkwijk,J. 2003. Tumor necrosis factor related apoptosis inducing ligand triggers apoptosis in dividing but not in differentiating human epidermal keratinocytes. J. Invest Dermatol. 121, 1433-1439.

  • Franssen,M.E., Smit,J.V., van Erp,P.E. & Van De Kerkhof,P.C. 2003. A multiparameter flow cytometric analysis of the effect of bexarotene on the epidermis of the psoriatic lesion. Br. J. Dermatol. 149, 506-512.

  • Pol,A., Bergers,M. & Schalkwijk,J. 2003. Comparison of antiproliferative effects of experimental and established antipsoriatic drugs on human keratinocytes, using a simple 96-well-plate assay. In Vitro Cell Dev. Biol. Anim 39, 36-42.

  • Zweers,M.C., Bristow,J., Steijlen,P.M., Dean,W.B., Hamel,B.C., Otero,M., Kucharekova,M., Boezeman,J.B. & Schalkwijk,J. 2003. Haploinsufficiency of TNXB is associated with hypermobility type of Ehlers-Danlos syndrome. Am. J. Hum. Genet. 73, 214-217.

  • Zeeuwen,P.L., Dale,B.A., de Jongh,G.J., Vlijmen-Willems,I.M., Fleckman,P., Kimball,J.R., Stephens,K. & Schalkwijk,J. 2003. The human cystatin M/E gene (CST6): exclusion as a candidate gene for harlequin ichthyosis. J. Invest Dermatol. 121, 65-68.

  • Kucharekova,M., Vissers,W.H., Schalkwijk,J.J., Van De Kerkhof,P.C. & van der Valk,P.G. 2003. Lack of upregulation of epidermal fatty acid binding protein in dithranol induced irritation. Eur. J. Dermatol. 13, 254-257.

  • Kucharekova,M., Hornix,M., Ashikaga,T., T'kint,S., de Jongh,G.J., Schalkwijk,J., Van De Kerkhof,P.C. & van der Valk,P.G. 2003. The effect of the PDE-4 inhibitor (cipamfylline) in two human models of irritant contact dermatitis. Arch. Dermatol. Res. 295, 29-32.

  • Pol,A., Pfundt,R., Zeeuwen,P., Molhuizen,H. & Schalkwijk,J. 2003. Transcriptional regulation of the elafin gene in human keratinocytes. J. Invest Dermatol. 120, 301-307.
   
Publications 2002 updown

  • Zeeuwen,P.L., Vlijmen-Willems,I.M., Hendriks,W., Merkx,G.F. & Schalkwijk,J. 2002. A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification. Hum. Mol. Genet. 11, 2867-2875.

  • Pol,A., van Ruissen,F. & Schalkwijk,J. 2002. Development of a keratinocyte-based screening model for antipsoriatic drugs using green fluorescent protein under the control of an endogenous promoter. J. Biomol. Screen. 7, 325-332.

  • Pol,A., Bergers,M., van Ruissen,F., Pfundt,R. & Schalkwijk,J. 2002. A simple technique for high-throughput screening of drugs that modulate normal and psoriasis-like differentiation in cultured human keratinocytes. Skin Pharmacol. Appl. Skin Physiol 15, 252-261.

  • Kucharekova,M., Schalkwijk,J., Van De Kerkhof,P.C. & Van De Valk,P.G. 2002. Effect of a lipid-rich emollient containing ceramide 3 in experimentally induced skin barrier dysfunction. Contact Dermatitis 46, 331-338.

  • van Rossum,M.M., Schalkwijk,J., Van De Kerkhof,P.C. & van Erp,P.E. 2002. Immunofluorescent surface labelling, flow sorting and culturing of putative epidermal stem cells derived from small skin punch biopsies. J. Immunol. Methods 267, 109-117.

  • Ophof,R., van Rheden,R.E., Von den,H.J., Schalkwijk,J. & Kuijpers-Jagtman,A.M. 2002. Oral keratinocytes cultured on dermal matrices form a mucosa-like tissue. Biomaterials 23, 3741-3748.

  • Zeeuwen,P.L., Vlijmen-Willems,I.M., Egami,H. & Schalkwijk,J. 2002. Cystatin M / E expression in inflammatory and neoplastic skin disorders. Br. J. Dermatol. 147, 87-94.

  • van Ruissen,F., Jansen,B.J., de Jongh,G.J., Zeeuwen,P.L. & Schalkwijk,J. 2002. A partial transcriptome of human epidermis. Genomics 79, 671-678.

  • Yoshida,N., Egami,H., Yamashita,J., Takai,E., Tamori,Y., Fujino,N., Kitaoka,M., Schalkwijk,J. & Ogawa,M. 2002. Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung. Oncol. Rep. 9, 495-501.

  • Glade,C.P., van der Vleuten,C.J., van Erp,P.E. & Van De Kerkhof,P.C. 2002. Flow cytometric assessment of clearance and relapse characteristics in psoriasis vulgaris after treatment with weekly clobetasol lotion under hydrocolloid occlusion versus twice-daily clobetasol ointment. Skin Pharmacol. Appl. Skin Physiol 15, 92-99.

  • van Ruissen,F., Jansen,B.J., de Jongh,G.J., Vlijmen-Willems,I.M. & Schalkwijk,J. 2002. Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries. FASEB J. 16, 246-248.

Publications 2001

 updown

  • van Erp,P.E. & Wingens,M. 2001. Does antisense make sense in dermatology? Acta Derm. Venereol. 81, 385-391.

  • van Ruissen,F., Jansen,B.J., de Jongh,G.J., Vlijmen-Willems,I.M. & Schalkwijk,J. 2002. Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries. FASEB J. 16, 246-248.

  • Schalkwijk,J., Zweers,M.C., Steijlen,P.M., Dean,W.B., Taylor,G., van Vlijmen,I.M., van Haren,B., Miller,W.L. & Bristow,J. 2001. A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency. N. Engl. J. Med. 345, 1167-1175.

  • van Rossum,M.M., van Erp,P.E. & van de Kerkhof,P.C. 2001. Treatment of psoriasis with a new combination of calcipotriol and betamethasone dipropionate: a flow cytometric study. Dermatology 203, 148-152.

  • Vandermeeren,M., Daneels,G., Bergers,M., Vlijmen-Willems,I., Pol,A., Geysen,J. & Schalkwijk,J. 2001. Development and application of monoclonal antibodies against SKALP/elafin and other trappin family members. Arch. Dermatol. Res. 293, 343-349.

  • Niessen,F.B., Andriessen,M.P., Schalkwijk,J., Visser,L. & Timens,W. 2001. Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars. J. Pathol. 194, 207-216.

  • Zeeuwen,P.L., Vlijmen-Willems,I.M., Jansen,B.J., Sotiropoulou,G., Curfs,J.H., Meis,J.F., Janssen,J.J., van Ruissen,F. & Schalkwijk,J. 2001. Cystatin M/E expression is restricted to differentiated epidermal keratinocytes and sweat glands: a new skin-specific proteinase inhibitor that is a target for cross-linking by transglutaminase. J. Invest Dermatol. 116, 693-701.

  • Pfundt,R., Vlijmen-Willems,I., Bergers,M., Wingens,M., Cloin,W. & Schalkwijk,J. 2001. In situ demonstration of phosphorylated c-jun and p38 MAP kinase in epidermal keratinocytes following ultraviolet B irradiation of human skin. J. Pathol. 193, 248-255.

  • Jansen,B.J., van Ruissen,F., de Jongh,G., Zeeuwen,P.L. & Schalkwijk,J. 2001. Serial analysis of gene expression in differentiated cultures of human epidermal keratinocytes. J. Invest Dermatol. 116, 12-22.
Publications 2000 updown

  • Castelijns,F.A., Gerritsen,M.J., van Erp,P.E. & van de Kerkhof,P.C. 2000. Cell-kinetic evidence for increased recruitment of cycling epidermal cells in psoriasis: the ratio of histone and Ki-67 antigen expression is constant. Dermatology 201, 105-110.

  • Latijnhouwers,M.A., de Jongh,G.J., Bergers,M., de Rooij,M.J. & Schalkwijk,J. 2000. Expression of tenascin-C splice variants by human skin cells. Arch. Dermatol. Res. 292, 446-454.

  • van Wetering,S., van der Linden,A.C., van Sterkenburg,M.A., Rabe,K.F., Schalkwijk,J. & Hiemstra,P.S. 2000. Regulation of secretory leukocyte proteinase inhibitor (SLPI) production by human bronchial epithelial cells: increase of cell-associated SLPI by neutrophil elastase. J. Investig. Med. 48, 359-366.

  • Mommers,J.M., van Rossum,M.M., van Erp,P.E. & van de Kerkhof,P.C. 2000. Changes in keratin 6 and keratin 10 (co-)expression in lesional and symptomless skin of spreading psoriasis. Dermatology 201, 15-20.

  • Emri,G., Wenczl,E., Van Erp,P., Jans,J., Roza,L., Horkay,I. & Schothorst,A.A. 2000. Low doses of UVB or UVA induce chromosomal aberrations in cultured human skin cells. J. Invest Dermatol. 115, 435-440.

  • Seegers,B.A., Glade,C.P., van Hooijdonk,C.A., van Erp,P.E., de Jongh,G.J. & van de Kerkhof,P.C. 2000. Flow-cytometric characterization of normal versus psoriatic epidermis using improved cell separation methodology. Exp. Dermatol. 9, 266-270.

  • van Rossum,M.M., Mommers,J.M., van Erp,P.E., Leyninger,E., Clucas,A. & van de Kerkhof,P.C. 2000. CD 2394, a novel synthetic retinoid, initiates an embryonic type of differentiation in hyperproliferative skin. Acta Derm. Venereol. 80, 98-101.

  • Pfundt,R., Wingens,M., Bergers,M., Zweers,M., Frenken,M. & Schalkwijk,J. 2000. TNF-alpha and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway. Arch. Dermatol. Res. 292, 180-187.

  • Seegers,B.A., Andriessen,M.P., van Hooijdonk,C.A., de Bakker,E.S., Vlijmen-Willems,I.M., Parker,G.L., van Erp,P.E. & van de Kerkhof,P.C. 2000. Pharmacological effects of a specific leukotriene B(4) receptor antagonist (VML 295) on blood leukocytes, cutaneous inflammation and epidermal proliferation. Skin Pharmacol. Appl. Skin Physiol 13,  75-85.

  • Castelijns,F.A., Gerritsen,M.J., van Erp,P.E. & van de Kerkhof,P.C. 2000. Efficacy of calcipotriol ointment applied under hydrocolloid occlusion in psoriasis. Dermatology 200, 25-30.

  • Mommers,J.M., Goossen,J.W., van de Kerkhof,P.C. & van Erp,P.E. 2000. Novel functional multiparameter flow cytometric assay to characterize proliferation in skin. Cytometry 42, 43-49.

  • van Rossum,M.M., Mommers,J.M., van de Kerkhof,P.C. & van Erp,P.E. 2000. Coexpression of keratins 13 and 16 in human keratinocytes indicates association between hyperproliferation-associated and retinoid-induced differentiation. Arch. Dermatol. Res. 292, 16-20.

  • van Wetering,S., van der Linden,A.C., van Sterkenburg,M.A., de Boer,W.I., Kuijpers,A.L., Schalkwijk,J. & Hiemstra,P.S. 2000. Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins. Am. J. Physiol Lung Cell Mol. Physiol 278, L51-L58.
Publications 1999 updown

  • Mommers,J.M., van Erp,P.E. & van De Kerkhof,P.C. 1999. Clobetasol under hydrocolloid occlusion in psoriasis results in a complete block of proliferation and in a rebound of lesions following discontinuation. Dermatology 199, 323-327.

  • Wingens,M., Pfundt,R., Vlijmen-Willems,I.M., van Hooijdonk,C.A., van Erp,P.E. & Schalkwijk,J. 1999. Sequence-specific inhibition of gene expression in intact human skin by epicutaneous application of chimeric antisense oligodeoxynucleotides. Lab Invest 79, 1415-1424.

  • Niessen,F.B., Spauwen,P.H., Schalkwijk,J. & Kon,M. 1999. On the nature of hypertrophic scars and keloids: a review. Plast. Reconstr. Surg. 104, 1435-1458.

  • van Rossum,M.M., Mommers,J.M., van Hooijdonk,C.A., van Erp,P.E. & van De Kerkhof,P.C. 1999. The response of distant uninvolved psoriatic skin to standardised injury is not different from that in normal skin. Skin Pharmacol. Appl. Skin Physiol 12, 271-275.

  • Mommers,J.M., ter Meulen,A.C., van Erp,P.E. & van De Kerkhof,P.C. 1999. Influence of tacalcitol on cell cycle kinetics of human keratinocytes following standardized injury. Skin Pharmacol. Appl. Skin Physiol  12, 174-181.

  • Castelijns,F.A., Gerritsen,M.J., Vlijmen-Willems,I.M., van Erp,P.E. & van De Kerkhof,P.C. 1999. The epidermal phenotype during initiation of the psoriatic lesion in the symptomless margin of relapsing psoriasis. J. Am. Acad. Dermatol. 40, 901-909.

  • Schalkwijk,J., Wiedow,O. & Hirose,S. 1999. The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core. Biochem. J. 340 ( Pt 3), 569-577.

  • Gerritsen,M.J., van Erp,P.E. & van De Kerkhof,P.C. 1999. Plasma membrane bound transglutaminase in the marginal zone of psoriatic skin. Clin. Exp. Dermatol. 24, 237-239.

  • Castelijns,F.A., Gerritsen,M.J., Vlijmen-Willems,I.M., van Erp,P.J. & van De Kerkhof,P.C. 1999. Proliferation is the main epidermal target in the treatment of psoriatic plaques with once daily application of tacalcitol ointment. Acta Derm. Venereol. 79, 111-114.

  • Mommers,J.M., van Rossum,M.M., van Hooijdonk,C.A., van Erp,P.E. & van De Kerkhof,P.C. 1999. Quantification of epidermal cell populations in the centre and margin of stable psoriatic plaques. Arch. Dermatol. Res. 291, 88-92.

  • Castelijns,F.A., Gerritsen,M.J., van Erp,P.E. & van De Kerkhof,P.C. 1999. Immunohistochemical assessment of keratin 16 on paraffin-embedded sections of normal and hyperproliferative skin: monoclonal antibodies Ks8.12 and LL025 in a comparative study. Arch. Dermatol. Res. 291, 59-63.
Publications 1998 updown

  • van Rossum,M.M., Mommers,J.M., van de Kerkhof,P.C., de Jongh,G.J., van Hooijdonk,C.A. & van Erp,P.E. 1998. Multi parameter flow cytometric assessment of regenerative epidermis with special reference to the antiproliferative effect of occlusion. Anal. Cell Pathol. 17, 157-165.

  • Castelijns,F.A., Ezendam,J., Latijnhouwers,M.A., Vlijmen-Willems,I.M., Zeeuwen,P.L., Gerritsen,M.J., van de Kerkhof,P.C. & van Erp,P.E. 1998. Epidermal cell kinetics by combining in situ hybridization and immunohistochemistry. Histochem. J. 30, 869-877.

  • Kuijpers,A.L., Van Pelt,J.P., Bergers,M., Boegheim,P.J., Den Bakker,J.E., Siegenthaler,G., van de Kerkhof,P.C. & Schalkwijk,J. 1998. The effects of oral liarozole on epidermal proliferation and differentiation in severe plaque psoriasis are comparable with those of acitretin. Br. J. Dermatol. 139, 380-389.

  • Andriessen,M.P., Niessen,F.B., van de Kerkhof,P.C. & Schalkwijk,J. 1998. Hypertrophic scarring is associated with epidermal abnormalities: an immunohistochemical study. J. Pathol. 186, 192-200.

  • Wingens,M., van Bergen,B.H., Hiemstra,P.S., Meis,J.F., Vlijmen-Willems,I.M., Zeeuwen,P.L., Mulder,J., Kramps,H.A., van Ruissen,F. & Schalkwijk,J. 1998. Induction of SLPI (ALP/HUSI-I) in epidermal keratinocytes. J. Invest Dermatol. 111, 996-1002.

  • Latijnhouwers,M.A., Bergers,M., Veenhuis,R.T., Beekman,B., Ankersmit-Ter Horst,M.F. & Schalkwijk,J. 1998. Tenascin-C degradation in chronic wounds is dependent on serine proteinase activity. Arch. Dermatol. Res. 290, 490-496.

  • Latijnhouwers,M.A., Bergers,M., Kuijpers,A.L., van der Vleuten,C.J., Dijkman,H., van de Kerkhof,P.C. & Schalkwijk,J. 1998. Tenascin-C is not a useful marker for disease activity in psoriasis. Acta Derm. Venereol. 78, 331-334.

  • Mommers,J.M., Castelijns,F.A., Seegers,B.A., van Rossum,M.M., van Hooijdonk,C.A., van Erp,P.E. & van de Kerkhof,P.C. 1998. The effect of long-term treatment with tacalcitol on the psoriatic epidermis. A flow cytometric analysis. Br. J. Dermatol. 139, 468-471.

  • Van Pelt,J.P., De Jong,E.M., Seijger,M.M., van Hooijdonk,C.A., De Bakker,E.S., Van Vlijmen,I.M., Parker,G.L., van Erp,P.E. & van de Kerkhof,P.C. 1998. Investigation on a novel and specific leukotriene B4 receptor antagonist in the treatment of stable plaque psoriasis. Br. J. Dermatol. 139, 396-402.

  • Latijnhouwers,M.A., Pfundt,R., de Jongh,G.J. & Schalkwijk,J. 1998. Tenascin-C expression in human epidermal keratinocytes is regulated by inflammatory cytokines and a stress response pathway. Matrix Biol. 17, 305-316.

  • Kuijpers,A.L., Pfundt,R., Zeeuwen,P.L., Molhuizen,H.O., Mariman,E.C., van de Kerkhof,P.C. & Schalkwijk,J. 1998. SKALP/elafin gene polymorphisms are not associated with pustular forms of psoriasis. Clin. Genet. 54, 96-101.

  • Glade,C.P., van der Vleuten,C.J., van Erp,P.E., De Jong,E.M. & van de Kerkhof,P.C. 1998. The epidermis of chronic idiopathic lichen planus during topical treatment with the vitamin D3 analogue KH 1060. Clin. Exp. Dermatol. 23, 14-18.

  • Glade,C.P., van Erp,P.E., Werner-Schlenzka,H. & van de Kerkhof,P.C. 1998. A clinical and flow cytometric model to study remission and relapse in psoriasis. Acta Derm. Venereol. 78, 180-185.

  • Wingens,M., van Hooijdonk,C.A., de Jongh,G.J., Schalkwijk,J. & van Erp,P.E. 1998. Flow cytometric and microscopic characterization of the uptake and distribution of phosphorothioate oligonucleotides in human keratinocytes. Arch. Dermatol. Res. 290, 119-125.

  • van Ruissen,F., Le,M., Carroll,J.M., van der Valk,P.G. & Schalkwijk,J. 1998. Differential effects of detergents on keratinocyte gene expression. J. Invest Dermatol. 110, 358-363.

  • Le,T.K., Schalkwijk,J., van de Kerkhof,P.C., van Haelst,U. & van der Valk,P.G. 1998. A histological and immunohistochemical study on chronic irritant contact dermatitis. Am. J. Contact Dermat. 9, 23-28.
Publications 1997 up

  • van Hooijdonk,C.A., Colbers,R.M., Piek,J. & van Erp,P.E. 1997. Demonstration of an Na+/H+ exchanger in mouse keratinocytes measured by the novel pH-sensitive fluorochrome SNARF-calcein. Cell Prolif. 30, 351-363.

  • Glade,C.P., van Erp,P.E., Boezeman,J.B. & van de Kerkhof,P.C. 1997. Multiparameter flow cytometry as a tool to evaluate antipsoriatic therapy. Br. J. Dermatol. 137, 367-375.

  • Andriessen,M.P., van den,B.J., Latijnhouwers,M.A., Bergers,M., van de Kerkhof,P.C. & Schalkwijk,J. 1997. Basal membrane heparan sulphate proteoglycan expression during wound healing in human skin. J. Pathol.  183, 264-271.

  • Yamamoto,S., Egami,H., Kurizaki,T., Ohmachi,H., Hayashi,N., Okino,T., Shibata,Y., Schalkwijk,J. & Ogawa,M. 1997. Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of the oesophagus. Br. J. Cancer 76, 1081-1086.

  • Zeeuwen,P.L., Hendriks,W., de Jong,W.W. & Schalkwijk,J. 1997. Identification and sequence analysis of two new members of the SKALP/elafin and SPAI-2 gene family. Biochemical properties of the transglutaminase substrate motif and suggestions for a new nomenclature. J. Biol. Chem. 272, 20471-20478.

  • Kuijpers,A.L., Schalkwijk,J., Rulo,H.F., Peperkamp,J.J., van de Kerkhof,P.C. & de Jong,E.M. 1997. Extremely low levels of epidermal skin-derived antileucoproteinase/elafin in a patient with impetigo herpetiformis. Br. J. Dermatol. 137, 123-129.

  • Feith,G.W., Bogman,M.J., Assmann,K.J., van Gompel,A.P., Schalkwijk,J., van Rooijen,N. & Koene,R.A. 1997. Decreased PMN accumulation and glomerular damage by clodronate liposome treatment in PMN-dependent anti-GBM nephritis in mice. Exp. Nephrol. 5, 301-304.

  • Le,T.K., De Mon,P., Schalkwijk,J. & van der Valk,P.G. 1997. Effect of a topical corticosteroid, a retinoid and a vitamin D3 derivative on sodium dodecyl sulphate induced skin irritation. Contact Dermatitis 37, 19-26.

  • Swart,G.W., van Groningen,J.J., van Ruissen,F., Bergers,M. & Schalkwijk,J. 1997. Transcription factor C/EBPalpha: novel sites of expression and cloning of the human gene. Biol. Chem. 378, 373-379.

  • Latijnhouwers,M., Bergers,M., Ponec,M., Dijkman,H., Andriessen,M. & Schalkwijk,J. 1997. Human epidermal keratinocytes are a source of tenascin-C during wound healing. J. Invest Dermatol. 108, 776-783.

  • van Pelt,J.P., de Jong,E.M., van Erp,P.E., Mitchell,M.I., Marder,P., Spaethe,S.M., van Hooijdonk,C.A., Kuijpers,A.L. & van de Kerkhof,P.C. 1997. The regulation of CD11b integrin levels on human blood leukocytes and leukotriene B4-stimulated skin by a specific leukotriene B4 receptor antagonist (LY293111). Biochem. Pharmacol. 53, 1005-1012.

  • Seyger,M.M., van den,B.J., Schalkwijk,J., van de Kerkhof,P.C. & de Jong,E.M. 1997. Altered distribution of heparan sulfate proteoglycans in psoriasis. Acta Derm. Venereol. 77, 105-109.

  • Kuijpers,A.L., Bergers,M., Siegenthaler,G., Zeeuwen,P.L., van de Kerkhof,P.C. & Schalkwijk,J. 1997. Skin-derived antileukoproteinase (SKALP) and epidermal fatty acid-binding protein (E-FABP): two novel markers of the psoriatic phenotype that respond differentially to topical steroid. Acta Derm. Venereol. 77, 14-19.
Organisation I Staff I Research I Articles I Protocols & Facilities I NCMLS I Courses & Seminars I Info I Links